The goal of our lab is to study the role of the cerebellum in neurological disorders. In particular, we focus on tremor and cerebellar ataxia, two very disabling conditions leading to incoordination of the hand and the gait. We use multiple approaches to study the disease mechanism of these disorders: patient brain pathology, animal models, human physiology, and stem cell-derived human neurons. Our studies aim to further our fundamental understanding of how movements are controlled by the cerebellum, toward the ultimate goal of rapidly translating this basic science knowledge into clinical use.
Lab website