Stanley J. Colcombe, PhD, is an internationally renowned researcher in the aging domain, including cognitive and cardiovascular fitness interventions targeted to offset neurocognitive decline in aging adults. Dr. Colcombe pioneered research demonstrating that cardiovascular fitness interventions result in positive changes in cognitive performance, as well as the structure and function of the aging brain. These findings have been replicated and extended several times and in many labs globally. His current focus is the impact of cardiovascular fitness on neurocognitive function in middle age, and how this affects the development of the aging brain; this is the focus of his most recent R01 award. Additionally, Dr. Colcombe is intensively interested in utilizing alternative implementations of standard (archival) MRI imaging data to investigate both clinically and non-clinically relevant alterations in neurocognitive performance across the lifespan and various psychiatric disorders.